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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 16.06
Human Site: T925 Identified Species: 22.08
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 T925 K L D I P T G T T P Q R K S Y
Chimpanzee Pan troglodytes XP_507923 1056 119132 T925 K L D I P T G T T P Q R K S Y
Rhesus Macaque Macaca mulatta XP_001087644 853 96218 C734 N L W T E R F C A L E E K C E
Dog Lupus familis XP_534964 1334 149091 M1207 K L D I P T G M T P Q R K N Y
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 M924 K L D I P T G M T P E R K K Y
Rat Rattus norvegicus O55165 796 89797 K677 G V N N S Q M K K R P T S A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 I980 E L E K M R E I C E K N Q E L
Frog Xenopus laevis P28025 1060 119314 T929 R N D V P T G T T P Q R R D Y
Zebra Danio Brachydanio rerio NP_775368 955 106984 T836 C D E A K G L T E S K A Q E Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 T932 K T Y A P T G T T P S K R D F
Honey Bee Apis mellifera XP_623508 706 80766 N587 M K V Y I A G N E Y E K C L N
Nematode Worm Caenorhab. elegans P46873 699 78760 I580 N E D E S R W I L P E M S M S
Sea Urchin Strong. purpuratus P46872 699 78679 S580 L E N V R E L S R E L R L S M
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 V935 C G N F N S M V L P C C E D L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 Q921 E K T L E S F Q Q D Q C C Q A
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 E980 S I E K P L H E H T R P E A S
Red Bread Mold Neurospora crassa P48467 928 102392 S809 R Q L V E Q N S A L K K E V A
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 100 13.3 86.6 N.A. 80 0 N.A. N.A. 6.6 66.6 6.6 N.A. 46.6 6.6 13.3 13.3
P-Site Similarity: 100 100 20 93.3 N.A. 86.6 20 N.A. N.A. 33.3 86.6 26.6 N.A. 66.6 20 20 33.3
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 6.6 N.A. N.A. 6.6 6.6 0
P-Site Similarity: 26.6 N.A. N.A. 26.6 40 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 0 6 0 0 12 0 0 6 0 12 12 % A
% Cys: 12 0 0 0 0 0 0 6 6 0 6 12 12 6 0 % C
% Asp: 0 6 36 0 0 0 0 0 0 6 0 0 0 18 0 % D
% Glu: 12 12 18 6 18 6 6 6 12 12 24 6 18 12 6 % E
% Phe: 0 0 0 6 0 0 12 0 0 0 0 0 0 0 6 % F
% Gly: 6 6 0 0 0 6 42 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 6 0 6 0 0 0 0 0 0 % H
% Ile: 0 6 0 24 6 0 0 12 0 0 0 0 0 0 0 % I
% Lys: 30 12 0 12 6 0 0 6 6 0 18 18 30 6 0 % K
% Leu: 6 36 6 6 0 6 12 0 12 12 6 0 6 6 12 % L
% Met: 6 0 0 0 6 0 12 12 0 0 0 6 0 6 6 % M
% Asn: 12 6 18 6 6 0 6 6 0 0 0 6 0 6 6 % N
% Pro: 0 0 0 0 42 0 0 0 0 48 6 6 0 0 0 % P
% Gln: 0 6 0 0 0 12 0 6 6 0 30 0 12 6 6 % Q
% Arg: 12 0 0 0 6 18 0 0 6 6 6 36 12 0 0 % R
% Ser: 6 0 0 0 12 12 0 12 0 6 6 0 12 18 12 % S
% Thr: 0 6 6 6 0 36 0 30 36 6 0 6 0 0 0 % T
% Val: 0 6 6 18 0 0 0 6 0 0 0 0 0 6 6 % V
% Trp: 0 0 6 0 0 0 6 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 6 0 0 0 0 0 6 0 0 0 0 30 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _